Blue Jays vs Orioles Prediction, Odds & Home Run Pick for Today's MLB Game

Want to get more Covers content? Add us as a preferred source on your Google account here.With two aging vets on the mound who don't miss many bats, we're riding with the Over in my Blue Jays vs. Orioles prediction. The Toronto Blue Jays head to Camden Yards (6:35 p.m. ET) as +100 underdogs at BET99. But I see more value in the total here, as I expect a lot of traffic on the base paths. Here are my free MLB picks for Tuesday, Sept. 22. Blue Jays vs Orioles predictions Blue Jays vs Orioles best bet: Over 7.5 Runs (+100) I'd price this closer to -110, so let's take advantage. The Toronto Blue Jays see a familiar face on the bump in Chris Bassitt tonight, and while he's been fine over his last two starts, his 4.96 xERA suggests Toronto should be able to get to him. I'm expecting the Blue Jays to manufacture some runs, with Bassitt owning the highest xBA (.279) and lowest K rate (16.4%) of his career this season. On the other side is Max Scherzer, and the Baltimore Orioles just tagged him for six earned runs 11 days ago. No matter how you slice it, we'll see offensive fireworks tonight. COVERS INTEL: Nobody is happier to see Bassitt than George Springer, who's hit two homers off him in his career and owns a .631 xSLG versus the righty in 26 plate appearances. Blue Jays vs Orioles same-game parlay (SGP) Springer has been absolutely owning Bassitt over his career, going 9-for-26 (.333 xBA) with a double and two homers off the veteran. Bassitt is also prone to walks, flying over this number in three of his last four starts. His 8.4% walk rate is the second-highest of his career. What does this all add up to if everything goes according to plan? An Over. Let's have some fun today. Blue Jays vs Orioles SGP George Springer 2+ H/R/RBI Chris Bassitt Over 1.5 walks Over 7.5 runs Alberta: Sports betting is now live! Regulated Alberta sports betting has officially launched, allowing sportsbooks to operate under provincial oversight. You can sign up and join BET99 — one of the best Alberta betting apps — now to get in on the Blue Jays action! Sign Up Now at Blue Jays vs Orioles home run pick: George Springer (+850) What's wrong with a little double-dip on Springer tonight? Not only does he boast strong numbers against Bassitt (two homers and a .631 xSLG), but six of his 15 homers this year have come off breaking balls, and we all know the veteran righty loves to throw the kitchen sink at hitters. If someone is going yard tonight, Springer is the most likely candidate. And at +850, we can't turn down that price. 2026 Transparency Record Best bets: 12-15, -1.87 units SGPs: 5-24, -0.60 units Blue Jays vs Orioles odds Moneyline: Toronto (+100) | Baltimore (-120) Run line: Toronto +1.5 (-200) | Baltimore -1.5 (+165) Over/Under: Over 7.5 (+100) | Under 7.5 (-125) Blue Jays vs Orioles trend The Over is 7-1 in Bassitt's last eight starts versus a team with a losing record. Find more MLB betting trends for Blue Jays vs. Orioles. How to watch Blue Jays vs Orioles and game info Location Oriole Park at Camden Yards, Baltimore, Md. Date Tuesday, Sept. 22, 2026 First pitch 6:35 p.m. ET TV Sportsnet, MASN Blue Jays starting pitcher Max Scherzer(3-8, 6.07 ERA) Orioles starting pitcher Chris Bassitt(8-5, 4.64 ERA) Blue Jays vs Orioles latest injuries Blue Jays vs Orioles weather Odds are correct at the time of publishing and are subject to change.Not intended for use in MA.Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links. This article originally appeared on Covers.com, read the full article here and view our best betting sites or check out our top sportsbook promos.