Padres vs Dodgers Prediction, Picks & Odds for Today's MLB Game

Want to get more Covers content? Add us as a preferred source on your Google account here.The Los Angeles Dodgers are slight 53% favorites over the San Diego Padres for today's series opener, and we have you covered with our top Padres vs. Dodgers predictions. Michael King gets the nod for the visitors, and my MLB picks think that's enough to give the edge in L.A., with first pitch set for 10:10 p.m. ET on TBS at Dodger Stadium. Who will win Padres vs Dodgers today: Padres moneyline For help understanding probabilities, see our odds calculator. Play the San Diego Padres at anything below 50% given their pitching advantage and red-hot lineup. They've won six of Michael King's last eight starts, a stretch during which he's posted a 1.98 ERA. The lineup has also been in peak form, pacing MLB with a .391 wOBA and 152 wRC+ in the last 14 days. There's also a motivational edge. The Los Angeles Dodgers have wrapped up the division and have secured a first-round bye, whereas the Padres are still jockeying for position atop the Wild Card race. COVERS INTEL: In his last eight starts, Michael King has induced a 17% soft contact rate. On the season, he ranks in the 85th percentile in average exit velocity and the 88th percentile in hard-hit rate. Padres vs Dodgers Over/Under pick: Under 8.5 The Padres typically play in low-scoring games with King on the bump, going 10-19-2 O/U across his 31 starts. L.A. is going with a bullpen game for this contest, but that's not such a bad thing given its strong recent performance. The Boys in Blue have a 3.18 FIP and league-best 2.76 SIERA in relief across the last 14 days and are fortified with Roki Sasaki's return to his natural role in the pen. San Diego has a deadly bullpen, sporting a 3.61 FIP on the year. All of the top arms, including Mason Miller, will be available after Monday's day of rest. Padres vs Dodgers home run prediction: Fernando Tatis Jr. Fernando Tatis Jr. has been scoring hot at the dish, leaving the yard five times in his last nine games. Dodger Stadium's 124 Park Factor for home runs means that there's an increased chance of Tatis continuing his fine form by popping a long ball. JD Yonke's 2026 Transparency Record ML/RL picks: 33-35, -6.6 units Over/Under picks: 40-29, +9.0 units Padres vs Dodgers weather The slight breeze out to center field could help long-ball hitters. Padres vs Dodgers odds Moneyline: Padres 47% | Dodgers 54% Run line: Padres +1.5 (66%) | Dodgers -1.5 (37%) Over/Under: Over 8.5 (48%) | Under 8.5 (53%) Padres vs Dodgers trend The Padres are 6-2 in Michael King's last eight starts. Find more MLB betting trends for Padres vs. Dodgers. How to watch Padres vs Dodgers and game info Location Dodger Stadium, Los Angeles, Calif. Date Tuesday, Sept. 22, 2026 First pitch 10:10 p.m. ET TV TBS Padres starting pitcher Michael King(12-9, 3.03 ERA) Dodgers starting pitcher Yoshinobu Yamamoto(14-8, 2.51 ERA) Padres vs Dodgers latest injuries Odds are correct at the time of publishing and are subject to change.Not intended for use in MA.Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links. This article originally appeared on Covers.com, read the full article here and view our best betting sites or check out our top sportsbook promos.